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Important: Protocol superseded July 2009 - see new version here at www.edren.co.uk.
That website is in development - you can ignore the 'This website is not ready' signs ONLY for the Transplant protocols. Others are not updated or fully transferred. |
Renal allograft biopsies are usually performed under USS guidance in x-ray department by the radiologist. Urgent biopsy requests should be discussed with a Consultant Radiologist.
All patients must have:
Consent - must be obtained by the doctor requesting the biopsy, and patients informed of risks:
Clotting screen - For biopsy to proceed results required:
Group and save
Heparin discontinued
Aspirin / Warfarin discontinued
Fluids only for a while before the procedure.
Results, Consent Form and Pathology Form must be attached to front of case notes for the attention of radiologist. If samples are required for EM and immunofluorescence then this must be clearly indicated on the request card. These are required if de novo / recurrence of a primary glomerulonephritis is suspected – consider in any biopsy more than 3 months post-transplant.
Pathology Department contacted and told of the biopsy and arrangements made to collect the specimens. INCLUDE request for electron microscopy and immunofluorescence in all samples over 3 months post transplant.
Pathology request forms must be filled in by the doctor requesting the biopsy. Unless otherwise stated it will be assumed that samples for light microscopy and frozen section are required. If sample for immunofluorescense or electron microscopy is required this must be stated on the form.
Out of hours, the on call Pathologist can be contacted via RIE switchboard
Post biopsy observations – every 15 mins for first 30 mins, every 30 mins for 2 hours, 4 hourly.
Transplant protocols developed on the Edinburgh Transplant Unit. This page first published January 2007 and last modified
NOTE that the accuracy of any statements in this information CANNOT be guaranteed. It is published in the belief that it is correct, and we endeavour to keep it so - but we do make mistakes. Furthermore, over some subjects there are differing opinions, or differing degrees of certainty. We have usually not attempted to discuss these here because the aim has been to provide an immediate and brief guide. In all areas, prior medical knowledge is assumed. The EdRenHANDBOOK is not suitable for use by those without such a background. Contact us by email or at the address given at the foot of the contents page with any comments or corrections.